Abstract To determine the efficacy and safety of Endostar combined with gemcitabine and cisplatin in the treatment of NSCLC, and provide evidence-based reference for clinical drug use. Retrieved from Cochrane Library, PubMed, Embase, ClinicalTrials, CNKI, Wanfang and VIP database, randomized controlled trials (RCT) were collected. Pooled standard mean differences (SMD) and 95% confidence intervals (CI) were analyzed using R software with a random-effects model. Data from a total of 27 RCTs were included, involving 1646 patients were analyzed. Results of meta-analysis showed that response rate and clinical benefit rate of trial group were significantly higher than those of control group. There was no statistical significance in the incidence of leucopenia, thrombocytopenia and gastrointestinal reaction between 2 groups. The results showed that Endostar combined with gemcitabine and cisplatin may generally improve therapeutic efficacy of NSCLC patients, without increasing the incidence of adverse reactions.

Abstract Although, wheat aleurone layer flour (WALF) is a good source of nutrients, it has certain disadvantages due relatively high levels of lipids and various of microorganisms and enzymes. Therefore, in the current study, the effect of superheated steam (SS) treatment on stabilization of WALF was investigated. This study aims to explore the effects of SS treatment on the degradation of free fatty acids of WALF under different conditions. The optimal process was obtained by an orthogonal optimization experiment, including optimized SS temperature, material moisture and treatment time. Results showed that the free fatty acids content of WALF significantly were decreased with SS treatment as the increase of treatment temperature, material moisture content and treatment times (p<0.05). Therefore, the optimum treatment conditions were selected during SS treatment. Compared with raw WALF, the activity of enzymes, total number of microbial colonies and phytate content in WALF were notably reduced after the SS of optimal condition. Nevertheless, its total dietary fiber content, insoluble dietary fiber content, pentosan content, total phenol content and total antioxidant capacity presented a remarkable increase (p<0.05).

Abstract Soy sauce wastewater has been produced in soy sauce production and consumption. To reuse this kind of water resource, the chemical oxygen demand (COD), colority should be removed or lowered. Biomimetic dynamic membrane (BDM), GO&Laccase@UF membrane, was prepared by filtering mixture of graphene oxide (GO) and laccase through ultrafiltration (UF) membrane. Compared to UF membrane, the prepared BDM showed great performance in removal of COD and colority, due to the higher laccase activity with existence of GO. The removal rate of colority reached ~80% by one step filtration operation. Moreover, the multiple cycle test evidenced that the value of COD and colority in the permeate after 5 consecutive cycles with the same GO&Laccase@UF membrane still meet the standard for reuse water. This work indicates the promising of BDM for wastewater from food industry.

The relationship between endogenous ethylene production and natural defoliation rate was examined in sugarcane cultivars with different natural defoliation traits. Ethylene production was examined at different positions on leaf sheaths and leaf scars at various sugarcane maturation stages using gas chromatography as an external standard method. During the sugarcane maturation process, ethylene production was greatest in the 2nd leaf sheath scar, followed by the 5th and 10th, in that order. It was also greatest during the early maturation stage, followed by the mid-maturation and harvest stages. Ethylene production of the leaf sheaths and leaf scars differed significantly among the sugarcane cultivars. Cultivars that defoliate easily produced significantly more ethylene than those that do not defoliate easily. The natural defoliation rates was greatest in the harvest stage, followed by mid-maturation and early maturation stage. Correlation analysis indicated that ethylene production was positively correlated with natural defoliation rates, particularly during early- and mid-maturation stages.